Acetyl L-Carnitine Pharmaceutical Grade and HPLC Tested Acetyl-L-Carnitine is the biologically active form of the amino acid L-Carnitine. Acetyl L-Carnitine occurs naturally in the body and it plays an important role in the production of acetylcholine, one of the body's key neurotransmitters. But the most important role of Acetyl L-Carnitine is the transport of fats into mitochondria (the powerhouses of the cells) where most of the cell's energy is produced. The most important anti-aging effect of Acetyl-L-Carnitine is working in conjunction with Coenzyme Q10 and Alpha Lipoic Acid to maintain the function of the mitochondria. When the mitochondria function dwindles, the cell will degenerate and become diseased. Mitochondria decay and the consequent decline in cellular energy production may be the most important causes of cellular decline in aging. Extensive research has shown the effectiveness of L-Carnitine in applications such as exercise, heart health, weight management, and brain anti-aging. A major cause of aging is the deterioration of the energy-producing components of the cell which results in reduced cellular metabolic activity, the accumulation of cellular debris, and eventual death of the cell. One of the most effective nutrients to maintain youthful cellular energy metabolism is the amino acid Acetyl-L-Carnitine, which functions to protect cells from the effects of aging. Acetyl L-Carnitine assists in the transport of fat through the cell membrane and into the mitochondria (the power-producing unit of the cell) within the cell, where these fats are utilized to produce the cellular energy ATP. In studies from the University of California at Berkeley (Hagen TM et al., 1998) Acetyl-L-Carnitine significantly reversed age-associated mitochondrial decay. Acetyl-L-Carnitine increased cellular respiration, and membrane potential. Recent attention has been placed upon its ability to protect and increase receptors in the brain that normally decline with age. As such, Acetyl-L-Carnitine is being used in high doses to treat senile dementias, and has also been shown to help remove lipofuscin, a potassium age buildup, a function that improves brain function. This could help improve short-term memory improves and mental focus. Acetyl-L-Carnitine is responsible for shuttling fats in and out of cells, some indications are that its use may benefit those on a diet to help lose weight. Acetyl-L-Carnitine has been shown to improve energy production within brain cells and is considered a neuroprotective agent because of its antioxidant action and membrane stabilizing effects. Several controlled clinical studies in Europe show that Acetyl-L-Carnitine slows down the natural course of Alzheimer's disease in many important respects. Acetyl L-Carnitine for Brain Function Acetyl L-Carnitine has been shown in numerous studies to protect cells throughout the body against age-related degeneration. A major cause of aging is the deterioration of the energy-producing components of the cell, which results in reduced cellular metabolic activity, the accumulation of cellular debris, and eventual death of the cell. Acetyl L-Carnitine facilitates the removal of excess short and medium chain fatty acids from the mitochondria, that accumulate during metabolism. There is extensive research data on the rejuvenating effects of Acetyl L-Carnitine on the brain, where improved mood, memory and cognition has been observed in response to Acetyl-L-Carnitine administration. By facilitating the youthful transport of fatty acids into the cell's mitochondria, Acetyl-L-Carnitine helps enable dietary fats to be converted to energy, which results in more youthful cellular function. Acetyl L-Carnitine has been used successfully as a nutritional adjunct in the treatment of Alzheimer's disease, diabetic peripheral neuropathy, and other diseases that affect the Central Nervous System (CNS) function such as age-associated memory impairment, depression, senility, cerebrovascular insufficiency, alcohol induced memory loss, and Down's syndrome. Numerous studies indicate that Acetyl L-Carnitine may have an anti-aging function in both the brain and the body. Acetyl L-Carnitine for Heart Disease L-Carnitine is approved as a drug in the United States to protect against muscle wasting diseases, including heart muscle weakness and low energy levels. The important role Acetyl L-Carnitine played in promoting cardiovascular health was dramatically demonstrated in research studies using laboratory animals. Scientists measured cell energy activity and respiration rates in the heart mitochondria of rats. Both cellular energy and respiration were depressed approximately 40% in the older rats. When Acetyl-L-Carnitine was administered, the heart rates of the older rats were almost completely restored to the metabolic function level of the younger control rats. This study showed the mechanism action of Acetyl L-Carnitine on the reversal of age-related cardiovascular deterioration. Acetyl L-Carnitine for Regenerating Nerves Neuorpathy, the deterioration of nerves, is a major health concern for the millions diagnosed with diabetics and the tens of millions of borderline diabetics. Diabetic neuropathy is an inevitable consequence of elevated glucose levels in the blood. In two related studies of diabetic nerve degeneration and neuropathy, Acetyl-L-Carnitine was shown to accelerate nerve regeneration after experimental injury. In the first study, doctors at the Hines VA Hospital in Illinois showed that diabetic rats treated with Acetyl-L-Carnitine maintained near normal nerve function without any adverse side effects. This study confirmed that Acetyl-L-Carnitine could accelerate nerve regeneration after experimental injury. In another study, doctors at the Nagoya University School of Medicine in Japan showed that Carnitine deficiency was closely related to the increased progression of diabetic neuropathy. These studies confirmed that Acetyl-L-Carnitine has great potential for the treatment of neurological diseases. Acetyl L-Carnitine is Pharmaceutical Grade and HPLC Tested. Each capsule contains Acetyl L-Carnitine 500mg. Free Ground Shipping on Orders over $79 for Supplements! Coupon THX2OFF50 for $2 off on orders over $50.
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